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Rabbit Anti-CD27/Gold Conjugated antibody (bs-23615R-Gold)
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說(shuō) 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23615R-Gold
英文名稱 Rabbit Anti-CD27/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的CD27抗體
別    名 CD 27; Cd27; CD27 antigen; CD27 molecule; CD27_MOUSE; CD27L receptor; LPFS2; MGC20393; OTTHUMP00000238557; S152; T cell activation antigen CD27; T cell antivation antigen S152; T-cell activation antigen CD27; T14; TNFRSF 7; TNFRSF7; TNFSF7; Tp 55; Tp55; Tumor necrosis factor receptor superfamily member 7.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  免疫學(xué)  干細(xì)胞  淋巴細(xì)胞  t-淋巴細(xì)胞  細(xì)胞因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD27
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Function:
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

Subunit:
Homodimer. Interacts with SIVA1 and TRAF2.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Found in most T-lymphocytes.

Post-translational modifications:
Phosphorylated.
O-glycosylated with core 1 or possibly core 8 glycans.

Similarity:
Contains 3 TNFR-Cys repeats.

Database links:

Entrez Gene: 939 Human

Entrez Gene: 21940 Mouse

Entrez Gene: 500318 Rat

Omim: 186711 Human

SwissProt: P26842 Human

SwissProt: P41272 Mouse

Unigene: 355307 Human

Unigene: 367714 Mouse

Unigene: 134200 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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